English term (edited): 5ˊ –leader –UTR –replicase –Structural genes

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Note added at 1 hr (2023-06-14 18:44:01 GMT)
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5ˊ: The 5ˊ (pronounced "five prime") refers to the 5' end of the viral genome. In molecular biology, DNA or RNA molecules have two ends: the 5' end and the 3' end. The 5' end is where the first nucleotide in the sequence is located.

Leader: The leader sequence is a region at the 5' end of the viral genome that precedes the main coding region. It often contains regulatory elements that control viral gene expression and replication.

UTR: UTR stands for Untranslated Region. The UTRs are non-coding regions found at both ends of the viral genome. They do not contain instructions for protein synthesis but play important roles in gene expression, translation, and replication. In this context, the 5' UTR refers to the region located at the 5' end of the viral genome.

Replicase: The replicase is an enzyme or a group of enzymes encoded by the viral genome. It is responsible for replicating the viral RNA and playing a crucial role in the viral replication cycle. The replicase gene is typically located after the UTRs and is involved in synthesizing new viral genomes.

Structural: The term "Structural" refers to the structural genes of the coronavirus, which were represented by the letters S, E, M, and N in the sequence "(S-E-M-N)-3ˊ UTR-poly(A)." These genes encode proteins that contribute to the structure and assembly of the virus.

So, the sequence "5ˊ –leader –UTR –replicase –Structural genes (S-E-M-N)" represents the arrangement of genomic regions at the 5' end of the COVID-19 genome, starting with the leader sequence, followed by the UTR, the replicase gene, and finally, the structural genes S, E, M, and N.







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Note added at 1 hr (2023-06-14 18:46:32 GMT)
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تعديل:
المُتَنَسِّخَة وليس المستنخسة